Yes. Silicone is naturally oily, so you may want to set your favorite clothing aside while you use Cimeosil. However, to minimize problems, only use a thin coating of Scar Gel (more is not better!), wipe away any excess and allow it to dry for 15 to 20 minutes before donning clothing. The Gel Sheeting has a protective coating on the non-skin side, so staining may be less likely.